Getting older, You are increasingly at risk of experiencing Alzheimer’s disease or a more familiar called “senile”. Alzheimer’s generally experienced by the vulnerable elderly above 65 years, but symptoms can start to appear a little bit since the age of 40. Until now the cause of Alzheimer’s disease actually is still a mystery. However, a number of medical researchers and health experts suspect that the germs that live in the brain may be a cause of Alzheimer’s. Refer to the explanation in the following reviews.
Overview of Alzheimer’s disease
Alzheimer’s disease was first discovered in 1906 by a doctor named Alois Alzheimer’s after observing the brain’s nerve cells patients that constrict causing missing memories gradually.
Alzheimer is a disease that attacks the brain’s cognitive functions so as to make a person difficult to remember, think, speak, even speaking. This degenerative disease also causes the behaviour to change people through daily activities.
So far, the medical world has not been able to appoint what would have been the cause of Alzheimer’s. They argued that the disease is most likely to emerge as a result of a combination of natural aging symptoms and buildup of beta-amyloid plaques in the brain.
Similarly with penyembuhnya drugs that have yet to be found. However, researchers continue to dig deeper about this disease.
Germ infection in the brain could be the cause of Alzheimer’s disease?
A study by the University of Bristol published in the online journal Frontiers in Aging Neuroscience found that the brains of people with Alzheimer’s tend to have the number and type of bacteria up to 7 times more than the brains of healthy people. Researchers concluded these findings observed the DNA of bacteria that exist in the brain of each sample research through a method called DNA sequencing.
A healthy person’s brain contains very few bacteria. The reason, the brain has a special seal on the back of the main blood vessels that are very difficult to penetrated by bacteria.
It means that if the brain is experiencing an increase in the type and population of bacteria, most likely the seal is no longer functioning as it should be to deter the entry of bacteria. It is found more likely to occur in people who are at risk of Alzheimer’s because of hereditary factors genetic.
“Alzheimer’s patients, the nerves in his brain suffered inflammation so that it will continue to constrict. This reaction is probably inflammation from bacterial infection, “explained David Emery, a member of the research.
However, it should be understood that this research scope is narrow. The research team only to compare the sample with the dead person with brain 8 Alzheimer’s and brain from cadaver 6 proven not risky or severe Alzheimer’s during his lifetime). Still, more research is needed again to be able to ascertain whether a bacterial infection in the brain could actually be the cause of Alzheimer’s.
Other possible causes of Alzheimer’s disease
This is not the first time to create the scientists suspect a bacterial infection can be a cause of Alzheimer’s. Previous studies have also found that people with Alzheimer’s on during his lifetime never infected by germs, such as bacteria other than certain fungi and viruses.
However, the theory of the cause of Alzheimer’s is the most popular to date is the buildup of beta-amyloid protein in the brain. In healthy people, excess beta-amyloid that exist in the brain will be broken up and distributed to all parts of the brain. But in Alzheimer’s patients, these proteins harden into plaques so as to prevent the nerve cells in the brain are working normally.
There is also a theory that mentions that there is a certain abnormalities in the brain that can cause Alzheimer’s disease. Alzheimer’s patients, tau, protein fibres in the brain that functions transporting nutrients into the cell’s suspected can not work properly. This disorder often occurs in people who have a form of the gene apolipoporotein E (APOE) on chromosome 19. This was agreed by the gene researchers have a risk of developing Alzheimer’s disease is higher than other genes.
In addition to the factors of a person’s lifestyle, genes can also affect the risk of Alzheimer’s disease. This involves eating patterns, physical activity, and social involvement.